ARCH Venture Management, LLC — 13F holdings

ARCH Venture Management, LLC reported 12 holdings worth $1.10B in its 13F filing for Q2 2026, filed August 14, 2026.

Largest positions

1. PBLS PARABILIS MEDICINES INC — $176M (16.0%)
2. BEAM BEAM THERAPEUTICS INC — $156M (14.2%)
3. RAPP RAPPORT THERAPEUTICS INC — $155M (14.1%)
4. SPTX SEAPORT THERAPEUTICS INC — $137M (12.4%)
5. ERAS Erasca Inc — $130M (11.8%)
6. VIR VIR BIOTECHNOLOGY INC — $129M (11.8%)
7. MAZE MAZE THERAPEUTICS INC — $123M (11.2%)
8. LYEL LYELL IMMUNOPHARMA INC — $45.5M (4.1%)
9. GENB Generate Biomedicines Inc — $32.8M (3.0%)
10. TXG 10X GENOMICS INC — $8.35M (0.8%)