Opaleye Management Inc. — 13F holdings

Opaleye Management Inc. reported 58 holdings worth $1.10B in its 13F filing for Q2 2026, filed August 14, 2026.

Largest positions

1. LQDA LIQUIDIA CORPORATION — $195M (17.7%)
2. ETON ETON PHARMACEUTICALS INC — $104M (9.4%)
3. HROW HARROW INC — $102M (9.2%)
4. IRON DISC MEDICINE INC — $62.5M (5.7%)
5. URGN UROGEN PHARMA LTD — $53.0M (4.8%)
6. APGE APOGEE THERAPEUTICS INC — $51.8M (4.7%)
7. MGTX MEIRAGTX HLDGS PLC — $48.0M (4.3%)
8. SLGL SOL-GEL TECHNOLOGIES LTD — $37.1M (3.4%)
9. RZLT REZOLUTE INC — $32.8M (3.0%)
10. TGTX TG THERAPEUTICS INC — $29.4M (2.7%)