Siren, L.L.C. — 13F holdings

Siren, L.L.C. reported 119 holdings worth $4.94B in its 13F filing for Q2 2026, filed August 13, 2026.

Largest positions

1. SRRK SCHOLAR ROCK HLDG CORP — $527M (10.7%)
2. KYMR KYMERA THERAPEUTICS INC — $337M (6.8%)
3. ERAS Erasca Inc — $209M (4.2%)
4. MANE VERADERMICS INC — $204M (4.1%)
5. TNGX TANGO THERAPEUTICS INC — $193M (3.9%)
6. RVMD REVOLUTION Medicines Inc — $169M (3.4%)
7. BCAX BICARA THERAPEUTICS INC — $166M (3.4%)
8. ARWR ARROWHEAD PHARMACEUTICALS IN — $140M (2.8%)
9. ONC BEONE MEDICINES LTD — $133M (2.7%)
10. EWTX EDGEWISE THERAPEUTICS INC — $129M (2.6%)