AMLX Amylyx Pharmaceuticals, Inc.: institutional ownership and insider trading
217 funds reported holding $2.22B of Amylyx Pharmaceuticals, Inc. in their latest 13F filings; in Q2 2026 funds net bought $13.0M, with 46 new positions and 13 funds selling out; over the last 12 months insiders bought $152K and sold $10.1M on the open market.
Famous investors holding AMLX
- Two Sigma (Two Sigma Investments): $10.7M, 0.0% of the portfolio
- Ken Griffin (Citadel Advisors): $3.40M, 0.0% of the portfolio
- D. E. Shaw (D. E. Shaw & Co.): $3.13M, 0.0% of the portfolio
Largest institutional holders of AMLX
- FMR LLC — $300M
- BlackRock, Inc. (BLK) — $159M
- PERCEPTIVE ADVISORS LLC — $150M
- TCG Crossover Management, LLC — $112M
- Commodore Capital LP — $101M
- Jupiter Topco LLC — $94.0M
- Saturn V Capital Management LP — $83.0M
- VANGUARD CAPITAL MANAGEMENT LLC — $75.9M
- VANGUARD GROUP INC — $70.1M
- JANUS HENDERSON GROUP PLC (JHG) — $69.3M
Recent AMLX insider trades
- Oct 5, 2026: Milne George M Jr sold 30,000 shares ($831K)
- Sep 10, 2026: Klee Justin B. sold 30,464 shares ($980K)
- Sep 10, 2026: Cohen Joshua B sold 30,464 shares ($981K)
- Sep 10, 2026: Mazzariello Gina sold 9,536 shares ($310K)
5%+ owners
- Perceptive Advisors LLC: 7.5% (Schedule 13G/A, filed May 15, 2026)