IONS IONIS PHARMACEUTICALS INC: institutional ownership and insider trading
525 funds reported holding $16.2B of IONIS PHARMACEUTICALS INC in their latest 13F filings; in Q2 2026 funds net bought $884M, with 64 new positions and 43 funds selling out; over the last 12 months insiders bought $1.06M and sold $120M on the open market; over its last four quarters it reported revenue of $874M and net income of −$565M.
IONS revenue and earnings
- Quarter ended Jun 30, 2026: revenue $268M, net income −$115M, EPS -0.69
- Quarter ended Mar 31, 2026: revenue $246M, net income −$92.5M, EPS -0.56
- Quarter ended Dec 31, 2025: revenue $203M, net income −$229M, EPS -1.41
- Quarter ended Sep 30, 2025: revenue $157M, net income −$129M, EPS -0.80
Famous investors holding IONS
- Tweedy, Browne (Tweedy, Browne Company): $181M, 13.7% of the portfolio
- Two Sigma (Two Sigma Investments): $496M, 0.4% of the portfolio
- Cathie Wood (ARK Investment Management): $23.8M, 0.2% of the portfolio
- Renaissance Technologies (Renaissance Technologies): $44.4M, 0.1% of the portfolio
- Izzy Englander (Millennium Management): $43.3M, 0.0% of the portfolio
- Ken Griffin (Citadel Advisors): $67.8M, 0.0% of the portfolio
- D. E. Shaw (D. E. Shaw & Co.): $30.5M, 0.0% of the portfolio
Largest institutional holders of IONS
- FMR LLC — $1.95B
- Capital World Investors — $1.72B
- VANGUARD GROUP INC — $1.30B
- BlackRock, Inc. (BLK) — $849M
- VANGUARD PORTFOLIO MANAGEMENT LLC — $623M
- WELLINGTON MANAGEMENT GROUP LLP — $607M
- VANGUARD CAPITAL MANAGEMENT LLC — $572M
- TWO SIGMA INVESTMENTS, LP — $496M
- ROYAL BANK OF CANADA (RY, RBMCF, RYLBF, RYPBF) — $490M
- STATE STREET CORP (STT, STT-PG) — $344M
Recent IONS insider trades
- Oct 16, 2026: Swayze Eric sold 53 shares ($2.31K)
- Oct 16, 2026: Devers Shannon L. sold 1,357 shares ($59.1K)
- Jul 31, 2026: Hayden Michael R bought 20,000 shares ($1.06M)
- Jul 7, 2026: Kordasiewicz Holly B. sold 362 shares ($30.5K)
5%+ owners
- Capital World Investors: 12.8% (Schedule 13G/A, filed May 14, 2026)
- Vanguard Capital Management: 5.1% (Schedule 13G, filed Apr 30, 2026)
Who owns the most IONS stock?
The largest institutional holders of IONIS PHARMACEUTICALS INC in the latest 13F filings are FMR LLC ($1.95B), Capital World Investors ($1.72B), VANGUARD GROUP INC ($1.30B).
Are insiders buying or selling IONS?
Over the last 12 months insiders bought $1.06M and sold $120M of IONIS PHARMACEUTICALS INC stock on the open market (SEC Form 4).
Which famous investors own IONS?
Tweedy, Browne, Two Sigma, Cathie Wood, Renaissance Technologies, Izzy Englander.
What was IONS's revenue last quarter?
IONIS PHARMACEUTICALS INC reported revenue of $268M for the quarter ended June 30, 2026, with net income of −$115M.
Which ETFs hold IONS?
126 ETFs and mutual funds hold it among their top 100 positions, including FDGRX, CSPAX, ANEFX, VGHAX.