PRAX Praxis Precision Medicines, Inc.: institutional ownership and insider trading
331 funds reported holding $13.2B of Praxis Precision Medicines, Inc. in their latest 13F filings; in Q2 2026 funds net bought $756M, with 55 new positions and 42 funds selling out; over the last 12 months insiders bought $0 and sold $11.1M on the open market.
Famous investors holding PRAX
- Ken Griffin (Citadel Advisors): $16.9M, 0.0% of the portfolio
- Two Sigma (Two Sigma Investments): $6.28M, 0.0% of the portfolio
- D. E. Shaw (D. E. Shaw & Co.): $3.39M, 0.0% of the portfolio
- Izzy Englander (Millennium Management): $333K, 0.0% of the portfolio
Largest institutional holders of PRAX
- Jupiter Topco LLC — $1.15B
- JANUS HENDERSON GROUP PLC (JHG) — $1.11B
- FMR LLC — $776M
- BlackRock, Inc. (BLK) — $768M
- PERCEPTIVE ADVISORS LLC — $682M
- BAKER BROS. ADVISORS LP — $587M
- Orbis Allan Gray Ltd — $512M
- VANGUARD PORTFOLIO MANAGEMENT LLC — $447M
- VANGUARD GROUP INC — $431M
- VANGUARD CAPITAL MANAGEMENT LLC — $414M
Recent PRAX insider trades
- Jun 24, 2026: DeSimone Jill sold 11,600 shares ($3.61M)
- Nov 20, 2025: Nemiroff Alex sold 25,130 shares ($4.85M)
- Nov 20, 2025: Mastrocola Lauren sold 13,600 shares ($2.61M)
- Oct 16, 2025: Atchinson Robert sold 313,910 shares ($33.2M)
Members of Congress trading PRAX
- Sep 29, 2026: Gilbert Ray Cisneros, Jr. bought $1.00K–$15.0K
- Jul 30, 2026: Gilbert Ray Cisneros, Jr. bought $1.00K–$15.0K
5%+ owners
- FMR LLC: 7.7% (Schedule 13G/A, filed May 6, 2026)
- Baker Bros. Advisors LP: 6.3% (Schedule 13G, filed May 15, 2026)
- ORBIS INVESTMENT MANAGEMENT LTD: 5.5% (Schedule 13G/A, filed Aug 14, 2026)
- Vanguard Capital Management: 5.1% (Schedule 13G, filed Apr 30, 2026)