SPRB SPRUCE BIOSCIENCES, INC.: institutional ownership and insider trading

68 funds reported holding $110M of SPRUCE BIOSCIENCES, INC. in their latest 13F filings; in Q2 2026 funds net bought $69.7M, with 39 new positions and 4 funds selling out; over the last 12 months insiders bought $0 and sold $0 on the open market.

Famous investors holding SPRB

Largest institutional holders of SPRB

  1. AIGH Capital Management LLC — $13.5M
  2. ORBIMED ADVISORS LLC — $10.8M
  3. BlackRock, Inc. (BLK) — $10.1M
  4. MILLENNIUM MANAGEMENT LLC — $8.69M
  5. Ikarian Capital, LLC — $6.55M
  6. VANGUARD CAPITAL MANAGEMENT LLC — $6.44M
  7. Alyeska Investment Group, L.P. — $4.41M
  8. GEODE CAPITAL MANAGEMENT, LLC — $3.81M
  9. ADAR1 Capital Management, LLC — $3.66M
  10. Cable Car Capital, LP — $3.24M

Recent SPRB insider trades

5%+ owners

All SPRB 13F holders · All SPRB insider trades