XBI holdings — State Street(R) SPDR(R) S&P(R) Biotech ETF
State Street(R) SPDR(R) S&P(R) Biotech ETF (XBI) held 161 positions with net assets of $10.7B as of June 30, 2026, according to its Form N-PORT report to the SEC. Its top 10 holdings make up 18.0% of the fund, led by State Street Global Advisors, APGE, MRNA.
XBI top holdings
- State Street Global Advisors — 5.87% ($631M)
- APGE Apogee Therapeutics Inc — 1.49% ($160M)
- MRNA Moderna Inc — 1.41% ($152M)
- TWST Twist Bioscience Corp — 1.41% ($151M)
- ORKA Oruka Therapeutics Inc — 1.38% ($148M)
- KYMR Kymera Therapeutics Inc — 1.36% ($146M)
- VKTX Viking Therapeutics Inc — 1.30% ($140M)
- PRAX Praxis Precision Medicines Inc — 1.29% ($139M)
- ERAS Erasca Inc — 1.27% ($136M)
- RVMD Revolution Medicines Inc — 1.20% ($129M)
- RYTM Rhythm Pharmaceuticals Inc — 1.20% ($129M)
- CGON CG oncology Inc — 1.20% ($129M)
- SLS SELLAS Life Sciences Group Inc — 1.19% ($128M)
- PCVX Vaxcyte Inc — 1.19% ($127M)
- DNTH Dianthus Therapeutics Inc — 1.18% ($127M)
- CYTK Cytokinetics Inc — 1.18% ($126M)
- NTRA Natera Inc — 1.16% ($125M)
- SRRK Scholar Rock Holding Corp — 1.16% ($124M)
- Roivant Sciences Ltd — 1.16% ($124M)
- MIRM Mirum Pharmaceuticals Inc — 1.16% ($124M)
- COGT Cogent Biosciences Inc — 1.14% ($123M)
- RARE Ultragenyx Pharmaceutical Inc — 1.14% ($122M)
- TVTX Travere Therapeutics Inc — 1.13% ($121M)
- Alkermes PLC — 1.11% ($119M)
- KRYS Krystal Biotech Inc — 1.10% ($118M)
What are XBI's top 10 holdings?
State Street Global Advisors (5.9%), APGE (1.5%), MRNA (1.4%), TWST (1.4%), ORKA (1.4%), KYMR (1.4%), VKTX (1.3%), PRAX (1.3%), ERAS (1.3%), RVMD (1.2%).
How many stocks are in XBI?
State Street(R) SPDR(R) S&P(R) Biotech ETF reported 161 holdings as of June 30, 2026.