SPTX Seaport Therapeutics, Inc.: institutional ownership and insider trading

56 funds reported holding $815M of Seaport Therapeutics, Inc. in their latest 13F filings; in Q2 2026 funds net bought $814M, with 54 new positions and 0 funds selling out; over the last 12 months insiders bought $20.0M and sold $0 on the open market.

SPTX revenue and earnings

Famous investors holding SPTX

Largest institutional holders of SPTX

  1. ARCH Venture Management, LLC — $137M
  2. GENERAL ATLANTIC, L.P. — $133M
  3. Sofinnova Investments, Inc. — $77.4M
  4. GOLDMAN SACHS GROUP INC (GS, GSCE, GS-PA, GS-PC, GS-PD) — $47.3M
  5. TRV GP VI, LLC — $44.8M
  6. CANADA PENSION PLAN INVESTMENT BOARD — $42.9M
  7. JPMORGAN CHASE & CO (JPM, AMJB, VYLD, JPM-PC, JPM-PD, JPM-PJ, JPM-PK, JPM-PL, JPM-PM) — $40.9M
  8. Foresite Capital Management VI LLC — $38.7M
  9. PRICE T ROWE ASSOCIATES INC /MD/ — $28.4M
  10. FMR LLC — $25.7M

Recent SPTX insider trades

5%+ owners

Who owns the most SPTX stock?

The largest institutional holders of Seaport Therapeutics, Inc. in the latest 13F filings are ARCH Venture Management, LLC ($137M), GENERAL ATLANTIC, L.P. ($133M), Sofinnova Investments, Inc. ($77.4M).

Are insiders buying or selling SPTX?

Over the last 12 months insiders bought $20.0M and sold $0 of Seaport Therapeutics, Inc. stock on the open market (SEC Form 4).

Which famous investors own SPTX?

Ken Griffin, Izzy Englander.

Which ETFs hold SPTX?

4 ETFs and mutual funds hold it among their top 100 positions, including JGLYX, PHLAX, JAFKX, DADGX.

All SPTX 13F holders · All SPTX insider trades